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Handbook on Estrogen Receptors in the Brain
Vijay Paramanik
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Description for Handbook on Estrogen Receptors in the Brain
Paperback. Num Pages: 60 pages. BIC Classification: MJN; PSAN; PSBC. Category: (P) Professional & Vocational. Dimension: 230 x 155. .
The present book covers estrogen, its receptors and estrogen mediated gene regulation in the brain. Further, it explains the mechanism of estrogen action and dysfunction leading to diseases. Briefly, estrogen mediates its multiple functions in the brain through two well-characterised receptors: ER and ERss. Upon binding with estrogen, ER recruits coregulators, which are responsible for tissue specific regulation. When coregulators activate the transcription of a particular gene, they become coactivators; when they repress the activity of particular gene, they are called corepressors. These coregulators make a bridge between the basal transcription machinery and the receptors by protein-protein interaction. Estrogen ... Read more
The present book covers estrogen, its receptors and estrogen mediated gene regulation in the brain. Further, it explains the mechanism of estrogen action and dysfunction leading to diseases. Briefly, estrogen mediates its multiple functions in the brain through two well-characterised receptors: ER and ERss. Upon binding with estrogen, ER recruits coregulators, which are responsible for tissue specific regulation. When coregulators activate the transcription of a particular gene, they become coactivators; when they repress the activity of particular gene, they are called corepressors. These coregulators make a bridge between the basal transcription machinery and the receptors by protein-protein interaction. Estrogen ... Read more
Product Details
Publisher
Nova Science Publishers Inc
Format
Paperback
Publication date
2016
Condition
New
Number of Pages
60
Place of Publication
New York, United States
ISBN
9781536100877
SKU
V9781536100877
Shipping Time
Usually ships in 5 to 9 working days
Ref
99-2
About Vijay Paramanik
The author has over a decade experience in the field of neurobiology and receptor biology. Dr Vijay Paramanik was born in Dhanbad, Jharkhand (a state in the eastern part) of India. Dr Paramanik completed his graduation in Zoology Honors with Botany and chemistry as other papers from Vinoba Bhave University, Hazaribag, Jharkhand, India. He did post-graduation in Zoology with specialization ... Read more
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