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Crumbling Genome: The Impact of Deleterious Mutations on Humans
Alexey S. Kondrashov
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Description for Crumbling Genome: The Impact of Deleterious Mutations on Humans
Paperback. Num Pages: 296 pages. BIC Classification: PSAK1. Category: (P) Professional & Vocational. Weight in Grams: 666.
A thought-provoking exploration of deleterious mutations in the human genome and their effects on human health and wellbeing Despite all of the elaborate mechanisms that a cell employs to handle its DNA with the utmost care, a newborn human carries about 100 new mutations, originated in their parents, about 10 of which are deleterious. A mutation replacing just one of the more than three billion nucleotides in the human genome may lead to synthesis of a dysfunctional protein, and this can be inconsistent with life or cause a tragic disease. Several percent of even young people suffer from diseases that ... Read more
A thought-provoking exploration of deleterious mutations in the human genome and their effects on human health and wellbeing Despite all of the elaborate mechanisms that a cell employs to handle its DNA with the utmost care, a newborn human carries about 100 new mutations, originated in their parents, about 10 of which are deleterious. A mutation replacing just one of the more than three billion nucleotides in the human genome may lead to synthesis of a dysfunctional protein, and this can be inconsistent with life or cause a tragic disease. Several percent of even young people suffer from diseases that ... Read more
Product Details
Publisher
John Wiley and Sons Ltd
Format
Paperback
Publication date
2017
Condition
New
Weight
665g
Number of Pages
296
Place of Publication
Hoboken, United States
ISBN
9781118952115
SKU
V9781118952115
Shipping Time
Usually ships in 7 to 11 working days
Ref
99-50
About Alexey S. Kondrashov
Alexey S. Kondrashov, PhD is Professor of Ecology and Evolutionary Biology at the University of Michigan, Ann Arbor. His research interests include evolution of sex and genetic recombination, properties of spontaneous deleterious mutations and of selection against them, and dynamics of genetic variation in natural and artificial populations.
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