Multiple Testing Procedures with Applications to Genomics
Dudoit, Sandrine; Laan, Mark J. Van Der
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Description for Multiple Testing Procedures with Applications to Genomics
Paperback. This book establishes the theoretical foundations of a general methodology for multiple hypothesis testing and discusses its software implementation in R and SAS. These are applied to a range of problems in biomedical and genomic research. Series: Springer Series in Statistics. Num Pages: 623 pages, biography. BIC Classification: PSAK. Category: (P) Professional & Vocational. Dimension: 234 x 156 x 32. Weight in Grams: 943.
This book establishes the theoretical foundations of a general methodology for multiple hypothesis testing and discusses its software implementation in R and SAS. These are applied to a range of problems in biomedical and genomic research, including identification of differentially expressed and co-expressed genes in high-throughput gene expression experiments; tests of association between gene expression measures and biological annotation metadata; sequence analysis; and genetic mapping of complex traits using single nucleotide polymorphisms. The procedures are based on a test statistics joint null distribution and provide Type I error control in testing problems involving general data generating distributions, null hypotheses, and ... Read more
This book establishes the theoretical foundations of a general methodology for multiple hypothesis testing and discusses its software implementation in R and SAS. These are applied to a range of problems in biomedical and genomic research, including identification of differentially expressed and co-expressed genes in high-throughput gene expression experiments; tests of association between gene expression measures and biological annotation metadata; sequence analysis; and genetic mapping of complex traits using single nucleotide polymorphisms. The procedures are based on a test statistics joint null distribution and provide Type I error control in testing problems involving general data generating distributions, null hypotheses, and ... Read more
Product Details
Format
Paperback
Publication date
2010
Publisher
Springer-Verlag New York Inc. United States
Number of pages
623
Condition
New
Series
Springer Series in Statistics
Number of Pages
590
Place of Publication
New York, NY, United States
ISBN
9781441923790
SKU
V9781441923790
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
Reviews for Multiple Testing Procedures with Applications to Genomics
From the reviews: "This book summarizes the recent work of Sandrine Dudoit and Mark van der Laan on multiple testing. It proposes a general framework for multiple testing procedures (MTPs) and introduces new concepts … . The authors also provide code for reproducing the results of some of the applications. … if one is looking ... Read more