Regulation of Alternative Splicing
Philippe . Ed(S): Jeanteur
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Description for Regulation of Alternative Splicing
Hardback. After a computer-based assessment of the frequency of alternative splicing, this book addresses mechanistic aspects, followed by examples of its involvement in important cellular processes. Finally, it raises the possibility of artificial modulation of alternative splicing by antisense nucleotides. Editor(s): Jeanteur, Philippe. Series: Progress in Molecular and Subcellular Biology / Marine Molecular Biotechnology. Num Pages: 258 pages, 77 black & white illustrations, 1 colour illustrations, 5 black & white tables, biography. BIC Classification: PSAK. Category: (P) Professional & Vocational; (UP) Postgraduate, Research & Scholarly; (UU) Undergraduate. Dimension: 235 x 155 x 19. Weight in Grams: 609.
The discovery in 1977 that genes are split into exons and introns has done away with the one gene - one protein dogma. Indeed, the removal of introns from the primary RNA transcript is not necessarily straightforward since there may be optional pathways leading to different messenger RNAs and consequently to different proteins. Examples of such an alternative splicing mechanism cover all fields of biology. Moreover, there are plenty of occurrences where deviant splicing can have pathological effects. Despite the high number of specific cases of alternative splicing, it was not until recently that the generality and extent of this ... Read more
The discovery in 1977 that genes are split into exons and introns has done away with the one gene - one protein dogma. Indeed, the removal of introns from the primary RNA transcript is not necessarily straightforward since there may be optional pathways leading to different messenger RNAs and consequently to different proteins. Examples of such an alternative splicing mechanism cover all fields of biology. Moreover, there are plenty of occurrences where deviant splicing can have pathological effects. Despite the high number of specific cases of alternative splicing, it was not until recently that the generality and extent of this ... Read more
Product Details
Format
Hardback
Publication date
2002
Publisher
Springer-Verlag Berlin and Heidelberg GmbH & Co. KG Germany
Number of pages
258
Condition
New
Series
Progress in Molecular and Subcellular Biology / Marine Molecular Biotechnology
Number of Pages
245
Place of Publication
Berlin, Germany
ISBN
9783540438335
SKU
V9783540438335
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
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