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Technologies for Detection of DNA Damage and Mutations
Gerd P. . Ed(S): Pfeifer
€ 197.66
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Description for Technologies for Detection of DNA Damage and Mutations
Hardback. Reviews a wide range of techniques used in mutagenesis research based on the polymerase chain reaction. This work features techniques such as: DNA damage analysis, DNA repair assays, and mutation detection are a few of the techniques featured. It includes chapters that present detailed experimental protocols benefiting researchers and students. Editor(s): Pfeifer, Gerd P. Num Pages: 441 pages, biography. BIC Classification: PSAK; PSB. Category: (P) Professional & Vocational; (UP) Postgraduate, Research & Scholarly; (UU) Undergraduate. Dimension: 254 x 178 x 27. Weight in Grams: 2470.
Man-made carcinogens, natural genotoxic agents in the environment, as well as ionizing and ultraviolet radiation can damage DNA and are a constant threat to genome integrity. Throughout the evolution oflife, complex DNA repair systems have developed in all living organisms to cope with this damage. Unrepaired DNA lesions can promote genetic alterations (mutations) that may be linked to an altered phenotype, and, if growth-controlling genes are involved, these mutations can lead to cell transformation and the development of malignant tumors. Proto oncogenes and tumor suppressor genes may be critical targets for DNA damaging agents. In a number of animal model ... Read more
Man-made carcinogens, natural genotoxic agents in the environment, as well as ionizing and ultraviolet radiation can damage DNA and are a constant threat to genome integrity. Throughout the evolution oflife, complex DNA repair systems have developed in all living organisms to cope with this damage. Unrepaired DNA lesions can promote genetic alterations (mutations) that may be linked to an altered phenotype, and, if growth-controlling genes are involved, these mutations can lead to cell transformation and the development of malignant tumors. Proto oncogenes and tumor suppressor genes may be critical targets for DNA damaging agents. In a number of animal model ... Read more
Product Details
Format
Hardback
Publication date
1996
Publisher
Springer Science+Business Media United States
Number of pages
441
Condition
New
Number of Pages
441
Place of Publication
, United States
ISBN
9780306452376
SKU
V9780306452376
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
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