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. Ed(S): Schousboe, Arne; Sonnewald, Ursula - The Glutamate/Gaba-Glutamine Cycle. Amino Acid Neurotransmitter Homeostasis.  - 9783319450940 - V9783319450940
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The Glutamate/Gaba-Glutamine Cycle. Amino Acid Neurotransmitter Homeostasis.

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Description for The Glutamate/Gaba-Glutamine Cycle. Amino Acid Neurotransmitter Homeostasis. Hardback. Editor(s): Schousboe, Arne; Sonnewald, Ursula. Series: Advances in Neurobiology. Num Pages: 416 pages, 13 black & white illustrations, 42 colour illustrations, 25 colour tables, biography. BIC Classification: PSAN. Category: (P) Professional & Vocational. Dimension: 235 x 155 x 24. Weight in Grams: 801.
Fundamental biochemical studies of basic brain metabolism focusing on the neuroactive amino acids glutamate and GABA combined with the seminal observation that one of the key enzymes, glutamine synthetase is localized in astroglial cells but not in neurons resulted in the formulation of the term “The Glutamate-Glutamine Cycle.” In this cycle glutamate released from neurons is taken up by surrounding astrocytes, amidated by the action of glutamine synthetase to glutamine which can be transferred back to the neurons. The conversion of glutamate to glutamine is like a stealth technology, hiding the glutamate molecule which would be highly toxic to neurons ... Read more

Product Details

Format
Hardback
Publication date
2016
Publisher
Springer International Publishing AG Switzerland
Number of pages
416
Condition
New
Series
Advances in Neurobiology
Number of Pages
416
Place of Publication
Cham, Switzerland
ISBN
9783319450940
SKU
V9783319450940
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15

About . Ed(S): Schousboe, Arne; Sonnewald, Ursula
Arne Schousboe obtained his M.Sc. in biochemistry from The University of Copenhagen in 1968 at a time where an M. Sc. was considered equivalent to a Ph.D. He subsequently (1978) earned his Doctor of Science (D. Sc.) degree also from University of Copenhagen. After a post-doc period with Dr. Eugene Roberts at the Department of Neuroscience, City of Hope National ... Read more

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