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Somatic Diversification of Immune Responses
. Ed(S): Kelsoe, Garnett; Flajnik, Martin
€ 127.18
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Description for Somatic Diversification of Immune Responses
Paperback. Editor(s): Kelsoe, Garnett; Flajnik, Martin. Series: Current Topics in Microbiology and Immunology. Num Pages: 231 pages, 23 black & white tables, biography. BIC Classification: MBGR; MJCM; PSF; PSG; PSVD. Category: (P) Professional & Vocational. Dimension: 234 x 156 x 12. Weight in Grams: 370.
Discovery of the mechanism for V(D)J hypermutation remains a basic goal of immunology despite the best efforts of many labo ratories. The existence of catalyzed, site-specific mutation and its exploitation for the somatic evolution of lymphocytes are re markable adaptations, yet since the discovery of hypermutation in 1970 (see cover), much hard work has generated little. Indeed, our knowledge of what is probably absolutely required for the mutator's action can be succinctly expressed: /g gene enhancers. Table 1 of Winter et a!.'s chapter puts into a historical perspec tive how our notions of the mutator have changed over the years. ... Read more
Discovery of the mechanism for V(D)J hypermutation remains a basic goal of immunology despite the best efforts of many labo ratories. The existence of catalyzed, site-specific mutation and its exploitation for the somatic evolution of lymphocytes are re markable adaptations, yet since the discovery of hypermutation in 1970 (see cover), much hard work has generated little. Indeed, our knowledge of what is probably absolutely required for the mutator's action can be succinctly expressed: /g gene enhancers. Table 1 of Winter et a!.'s chapter puts into a historical perspec tive how our notions of the mutator have changed over the years. ... Read more
Product Details
Format
Paperback
Publication date
2011
Publisher
Springer-Verlag Berlin and Heidelberg GmbH & Co. KG Germany
Number of pages
231
Condition
New
Series
Current Topics in Microbiology and Immunology
Number of Pages
221
Place of Publication
Berlin, Germany
ISBN
9783642719868
SKU
V9783642719868
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
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