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Chiral Separations
. Ed(S): Gubitz, Gerald; Schmid, Martin G.
€ 130.86
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Description for Chiral Separations
Hardback. Details chromatographic and electroseparation techniques developed for chiral separations on an analytical scale. This text presents procedures as either general methods or as specific applications to substance classes and special compounds, with emphasis on high performance liquid chromatography and capillary electrophoresis techniques. Editor(s): Gubitz, Gerald; Schmid, Martin G. Series: Methods in Molecular Biology. Num Pages: 432 pages, biography. BIC Classification: PDN; PSD. Category: (P) Professional & Vocational; (UP) Postgraduate, Research & Scholarly; (UU) Undergraduate. Dimension: 235 x 155 x 32. Weight in Grams: 912.
Many compounds of biological and pharmacological interest are as- metric and show optical activity. Approximately 40% of the drugs in use are known to be chiral and only about 25% are administered as pure enantiomers. It is well established that the pharmacological activity is mostly restricted to one of the enantiomers (eutomer). In several cases, unwanted side effects or even toxic effects may occur with the inactive enantiomer (distomer). Even if the side effects are not that drastic, the inactive enantiomer has to be meta- lized, which represents an unnecessary burden for the organism. The admin- tration of pure, pharmacologically ... Read more
Many compounds of biological and pharmacological interest are as- metric and show optical activity. Approximately 40% of the drugs in use are known to be chiral and only about 25% are administered as pure enantiomers. It is well established that the pharmacological activity is mostly restricted to one of the enantiomers (eutomer). In several cases, unwanted side effects or even toxic effects may occur with the inactive enantiomer (distomer). Even if the side effects are not that drastic, the inactive enantiomer has to be meta- lized, which represents an unnecessary burden for the organism. The admin- tration of pure, pharmacologically ... Read more
Product Details
Format
Hardback
Publication date
2003
Publisher
Humana Press Inc. United States
Number of pages
432
Condition
New
Series
Methods in Molecular Biology
Number of Pages
432
Place of Publication
Totowa, NJ, United States
ISBN
9781588291509
SKU
V9781588291509
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
Reviews for Chiral Separations
"It is an excellent book, and can be recommended for every laboratory involved in the synthesis and analysis of chiral compounds. Moreover, the editors have succeeded in getting internationally known leading experts to write the contributions." -Angewandte Chemie "...will undoubtedly be of value to those who need to find useful ways to carry ... Read more