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Endoplasmic Reticulum Stress in Health and Disease
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Description for Endoplasmic Reticulum Stress in Health and Disease
Hardcover. This book explores the pathophysiology of ER stress, covering its molecular bases, the emerging relevance of ER-mitochondria cross-talk, signaling pathways and cellular responses, including the adaptive Unfolded Protein Response, autophagy and cell death. Editor(s): Agostinis, Patrizia; Afshin, Samali. Num Pages: 460 pages, biography. BIC Classification: MBGR; MJCM; PSD; PSF. Category: (P) Professional & Vocational. Dimension: 242 x 160 x 30. Weight in Grams: 798.
The Endoplasmic Reticulum (ER) is an organelle with extraordinary signaling and homeostatic functions. It is the organelle responsible for protein folding, maturation, quality control and trafficking of proteins destined for the plasma membrane or for secretion into the extracellular environment. Failure, overloading or malfunctioning of any of the signaling or quality control mechanisms occurring in the ER may provoke a stress condition known as ‘ER stress’. Accumulating evidence indicates that ER stress may dramatically perturb interactions between the cell and its environment, and contribute to the development of human diseases, ranging from metabolic diseases and cancer to neurodegenerative diseases, or ... Read more
The Endoplasmic Reticulum (ER) is an organelle with extraordinary signaling and homeostatic functions. It is the organelle responsible for protein folding, maturation, quality control and trafficking of proteins destined for the plasma membrane or for secretion into the extracellular environment. Failure, overloading or malfunctioning of any of the signaling or quality control mechanisms occurring in the ER may provoke a stress condition known as ‘ER stress’. Accumulating evidence indicates that ER stress may dramatically perturb interactions between the cell and its environment, and contribute to the development of human diseases, ranging from metabolic diseases and cancer to neurodegenerative diseases, or ... Read more
Product Details
Format
Hardback
Publication date
2012
Publisher
Springer Netherlands
Number of pages
350
Condition
New
Number of Pages
452
Place of Publication
Dordrecht, Netherlands
ISBN
9789400743502
SKU
V9789400743502
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
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