Phosphoinositides I: Enzymes of Synthesis and Degradation
. Ed(S): Balla, Tamas; Wymann, Matthias; York, John D.
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Description for Phosphoinositides I: Enzymes of Synthesis and Degradation
Hardback. Phosphoinositides play a major role in cellular signaling and membrane organization. This book elucidates the crucial mechanisms that control the dynamics of phosphoinositide conversion. It focuses on phosphoinositide 3-kinases and 3-phosphatases, and presents therapeutic developments in human disease. Editor(s): Balla, Tamas; Wymann, Matthias; York, John D. Series: Subcellular Biochemistry. Num Pages: 372 pages, 3 black & white tables, 4 colour tables, biography. BIC Classification: MFCC; PSF. Category: (P) Professional & Vocational. Dimension: 235 x 155 x 25. Weight in Grams: 652.
Phosphoinositides play a major role in cellular signaling and membrane organization. During the last three decades we have learned that enzymes turning over phosphoinositides control vital physiological processes and are involved in the initiation and progression of cancer, inflammation, neurodegenerative, cardiovascular, metabolic disease and more. In two volumes, this book elucidates the crucial mechanisms that control the dynamics of phosphoinositide conversion. Starting out from phosphatidylinositol, a chain of lipid kinases collaborates to generate the oncogenic lipid phosphatidylinositol(3,4,5)-trisphosphate. For every phosphate group added, there are specific lipid kinases – and phosphatases to remove it. Additionally, phospholipases can cleave off the inositol ... Read more
Phosphoinositides play a major role in cellular signaling and membrane organization. During the last three decades we have learned that enzymes turning over phosphoinositides control vital physiological processes and are involved in the initiation and progression of cancer, inflammation, neurodegenerative, cardiovascular, metabolic disease and more. In two volumes, this book elucidates the crucial mechanisms that control the dynamics of phosphoinositide conversion. Starting out from phosphatidylinositol, a chain of lipid kinases collaborates to generate the oncogenic lipid phosphatidylinositol(3,4,5)-trisphosphate. For every phosphate group added, there are specific lipid kinases – and phosphatases to remove it. Additionally, phospholipases can cleave off the inositol ... Read more
Product Details
Format
Hardback
Publication date
2012
Publisher
Springer Netherlands
Number of pages
372
Condition
New
Series
Subcellular Biochemistry
Number of Pages
356
Place of Publication
Dordrecht, Netherlands
ISBN
9789400730113
SKU
V9789400730113
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
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