×


 x 

Shopping cart
Richard Durrett - Probability Models for DNA Sequence Evolution - 9780387781686 - V9780387781686
Stock image for illustration purposes only - book cover, edition or condition may vary.

Probability Models for DNA Sequence Evolution

€ 219.51
FREE Delivery in Ireland
Description for Probability Models for DNA Sequence Evolution Hardback. This book presents mathematical techniques for understanding sequence evolution. The theory is developed in close connection with data from more than 60 experimental studies that illustrate the use of these results. Series: Probability and its Applications. Num Pages: 443 pages, biography. BIC Classification: PBT; PSAJ; PSAK1. Category: (P) Professional & Vocational; (UP) Postgraduate, Research & Scholarly; (UU) Undergraduate. Dimension: 244 x 164 x 30. Weight in Grams: 614.

Our basic question is: Given a collection of DNA sequences, what underlying forces are responsible for the observed patterns of variability? To approach this question we introduce and analyze a number of probability models: the Wright-Fisher model, the coalescent, the infinite alleles model, and the infinite sites model. We study the complications that come from nonconstant population size, recombination, population subdivision, and three forms of natural selection: directional selection, balancing selection, and background selection. These theoretical results set the stage for the investigation of various statistical tests to detect departures from "neutral evolution". The final chapter studies the evolution of ... Read more

Throughout the book, the theory is developed in close connection with data from more than 60 experimental studies from the biology literature that illustrate the use of these results. This book is written for mathematicians and for biologists alike. We assume no previous knowledge of concepts from biology and only a basic knowledge of probability: a one semester undergraduate course and some familiarity with Markov chains and Poisson processes.

Show Less

Product Details

Format
Hardback
Publication date
2008
Publisher
Springer-Verlag New York Inc. United States
Number of pages
443
Condition
New
Series
Probability and its Applications
Number of Pages
431
Place of Publication
New York, NY, United States
ISBN
9780387781686
SKU
V9780387781686
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15

About Richard Durrett
Rick Durrett received his Ph.D. in operations research from Stanford University in 1976. He taught in the UCLA mathematics department before coming to Cornell in 1985. He is the author of six books and 125 research papers, and is the academic father of more than 30 Ph.D. students. His current interests are the use of probability models in genetics and ... Read more

Reviews for Probability Models for DNA Sequence Evolution
From the reviews: This book serves as an introduction to, and a compilation of, results in the new and growing field of probability theory for DNA evolution. The author is a probabilist, but he has made an effort to appeal to biologists and mathematicians alike. Biologists will find in this book those methods used for studying DNA variability that ... Read more

Goodreads reviews for Probability Models for DNA Sequence Evolution


Subscribe to our newsletter

News on special offers, signed editions & more!