.png){kind=logo}
Stock image for illustration purposes only - book cover, edition or condition may vary.
Total Synthesis of Bioactive Natural Products by Palladium-Catalyzed Domino Cyclization of Allenes and Related Compounds
Shinsuke Inuki
€ 127.10
FREE Delivery in Ireland
Description for Total Synthesis of Bioactive Natural Products by Palladium-Catalyzed Domino Cyclization of Allenes and Related Compounds
Hardback. This book details efficient synthetic approaches for biologically active compounds. It describes novel methodologies for highly efficient construction of functionalized heterocycles by palladium-catalyzed domino cyclization of allenes and related compounds. Series: Springer Theses. Num Pages: 122 pages, biography. BIC Classification: PNRD; PSB. Category: (P) Professional & Vocational. Dimension: 234 x 156 x 7. Weight in Grams: 356.
The author has developed novel methodologies for highly efficient construction of functionalized heterocycles by palladium-catalyzed domino/cascade cyclization of allenes and related compounds containing appropriate nucleophilic group(s). Based on these methodologies, enantioselective total syntheses of bioactive natural products, pachastrissamine (26% overall yield in seven steps), lysergic acid (4.0% overall yield in fifteen steps), lysergol (3.6% overall yield in fifteen steps) and isolysergol (8.2% overall yield in eleven steps) have been achieved. These are more facile synthetic route than those previously reported. These findings would contribute to the development of efficient synthetic methods for biologically active compounds containing a complex structure.
The author has developed novel methodologies for highly efficient construction of functionalized heterocycles by palladium-catalyzed domino/cascade cyclization of allenes and related compounds containing appropriate nucleophilic group(s). Based on these methodologies, enantioselective total syntheses of bioactive natural products, pachastrissamine (26% overall yield in seven steps), lysergic acid (4.0% overall yield in fifteen steps), lysergol (3.6% overall yield in fifteen steps) and isolysergol (8.2% overall yield in eleven steps) have been achieved. These are more facile synthetic route than those previously reported. These findings would contribute to the development of efficient synthetic methods for biologically active compounds containing a complex structure.
Product Details
Format
Hardback
Publication date
2011
Publisher
Springer Verlag, Japan Japan
Number of pages
122
Condition
New
Series
Springer Theses
Number of Pages
106
Place of Publication
Tokyo, Japan
ISBN
9784431540427
SKU
V9784431540427
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
Reviews for Total Synthesis of Bioactive Natural Products by Palladium-Catalyzed Domino Cyclization of Allenes and Related Compounds
From the reviews: “The target audience … includes practicing organic chemists with interests in synthesis, and those with specific interests in palladium-catalysed organic reactions, and as such is suited to graduate level and above. … is well-written and provides plenty of food for thought for specialists in palladium(II) chemistry … . the book also benefits from a comprehensive experimental ... Read more