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Two-Hybrid Systems
Paul N. . Ed(S): Macdonald
€ 126.88
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Description for Two-Hybrid Systems
Paperback. Designed to appeal to a broad range of scientists using two-hybrid systems in experimental biology, this book provides the basic methodologies for working with the yeast two-hybrid system. Editor(s): MacDonald, Paul N. Series: Methods in Molecular Biology. Num Pages: 336 pages, biography. BIC Classification: PSD. Category: (P) Professional & Vocational; (UP) Postgraduate, Research & Scholarly; (UU) Undergraduate. Dimension: 229 x 152 x 19. Weight in Grams: 1140.
Many, if not all, essential biological processes require selective interactions between proteins. Complex signaling systems require sequential, ordered protein-protein interactions at essentially all levels of the signaling cascade. For example, peptide hormones interact with selective membrane receptor proteins, and autophosphorylation of the receptor then recruits other key regulatory proteins that initiate kinase cascades in which each phosphorylation event requires selective recognition of the protein substrate. The ultimate signaling effect, in many cases, is the regulation of RNA polymerase II-directed transcr- tion in the nucleus, a process that involves numerous, multiprotein complexes important for transcription initiation, elongation, termination, and reinitiation. Defining, ... Read more
Many, if not all, essential biological processes require selective interactions between proteins. Complex signaling systems require sequential, ordered protein-protein interactions at essentially all levels of the signaling cascade. For example, peptide hormones interact with selective membrane receptor proteins, and autophosphorylation of the receptor then recruits other key regulatory proteins that initiate kinase cascades in which each phosphorylation event requires selective recognition of the protein substrate. The ultimate signaling effect, in many cases, is the regulation of RNA polymerase II-directed transcr- tion in the nucleus, a process that involves numerous, multiprotein complexes important for transcription initiation, elongation, termination, and reinitiation. Defining, ... Read more
Product Details
Format
Paperback
Publication date
2001
Publisher
Humana Press Inc. United States
Number of pages
336
Condition
New
Series
Methods in Molecular Biology
Number of Pages
336
Place of Publication
Totowa, NJ, United States
ISBN
9780896038080
SKU
V9780896038080
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
Reviews for Two-Hybrid Systems
"The utility of the technique makes this book worthwhile since all the information necessary to get started is included. Anyone should be able to start using the two-hybrid system in their lab using this book as a guide. The book is written for all levels of expertise from student to senior investigator. Each chapter is written by an expert in ... Read more