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Chemistry and Biology of Serpins
. Ed(S): Church, Frank C.; Cunningham, Dennis D.; Ginsburg, David; Hoffman, Maureane R. (Duke University, And Durham Va Medical Centers, Usa); Stone,
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Description for Chemistry and Biology of Serpins
Paperback. Proceedings of an International Symposium held in Chapel Hill, North Carolina, April 13-16, 1996 Editor(s): Church, Frank C.; Cunningham, Dennis D.; Ginsburg, David; Hoffman, Maureane R. (Duke University, and Durham VA Medical Centers, USA); Stone, Stuart R.; Tollefsen, Douglas M. Series: Advances in Experimental Medicine and Biology. Num Pages: 358 pages, biography. BIC Classification: MF; PSB; PSV. Category: (P) Professional & Vocational. Dimension: 254 x 178 x 20. Weight in Grams: 721.
Serpins (serine protease inhibitors) are a superfamily of proteins whose physiologi- cal action is primarily targeted to inhibiting serine proteases. There are instances where serpins are not inhibitors (and can carry steroid hormones for instance), yet key structural and functional elements found in all serpins are maintained in these 'non-inhibitor' ser- pins. Many serpins have well-described biological properties which influence pathophysi- ological events, including: antithrombin (historically called antithrombin III), ai-protease inhibitor (historically called ai-antitrypsin), and plasminogen activator inhibitor-I, just to mention a few. A deficiency or defect in antithrombin leads to venous thromboembolic disease, while a deficiency or defect in ... Read more
Serpins (serine protease inhibitors) are a superfamily of proteins whose physiologi- cal action is primarily targeted to inhibiting serine proteases. There are instances where serpins are not inhibitors (and can carry steroid hormones for instance), yet key structural and functional elements found in all serpins are maintained in these 'non-inhibitor' ser- pins. Many serpins have well-described biological properties which influence pathophysi- ological events, including: antithrombin (historically called antithrombin III), ai-protease inhibitor (historically called ai-antitrypsin), and plasminogen activator inhibitor-I, just to mention a few. A deficiency or defect in antithrombin leads to venous thromboembolic disease, while a deficiency or defect in ... Read more
Product Details
Format
Paperback
Publication date
2012
Publisher
Springer-Verlag New York Inc. United States
Number of pages
358
Condition
New
Series
Advances in Experimental Medicine and Biology
Number of Pages
358
Place of Publication
New York, NY, United States
ISBN
9781461374619
SKU
V9781461374619
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
Reviews for Chemistry and Biology of Serpins
`The editors have succeeded in producing a volume of work which provides many answers to questions, asked and unasked, about a critically important field of biologic research. It should be in the library of any scientist with an interest in human physiology; it would be useful to many other researchers as well.' Chemtracts ... Read more