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Syndromes of Hormone Resistance on the Hypothalamic-Pituitary-Thyroid Axis
Paolo . Ed(S): Beck-Peccoz
€ 126.94
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Description for Syndromes of Hormone Resistance on the Hypothalamic-Pituitary-Thyroid Axis
Paperback. Truly unique cutting edge state of the art information on basic and clinical research. A great help for the clinician to diagnose and treat this uncommon hormone resistance. Basic scientists learn how much has been discovered on the mechanism of hormone action from the mutations of the various genes involved to thyroid hormones and TSH. Editor(s): Beck-Peccoz, Paolo. Series: Endocrine Updates. Num Pages: 206 pages, 45 black & white illustrations, biography. BIC Classification: MJGD; PSAN; PSV; PSVD. Category: (P) Professional & Vocational. Dimension: 235 x 155 x 11. Weight in Grams: 326.
The exponential growth in our knowledge on the pathophysiology of hypothalamic-pituitary-thyroid axis and, in particular, of thyroid hormone action, largely stems from the studies on the various syndromes of resistance to the hormones involved in the function of the axis. These syndromes essentially encompass two forms, i. e. the resistance to thyroid hormones and that to TSH action. The contribution of molecular biology has been fundamental in understanding the etiology of these different thyroid disorders and led to the discovery of new pathogenetic mechanisms, e. g. the dominant negative effects of a mutant protein on the normal one. In this ... Read more
The exponential growth in our knowledge on the pathophysiology of hypothalamic-pituitary-thyroid axis and, in particular, of thyroid hormone action, largely stems from the studies on the various syndromes of resistance to the hormones involved in the function of the axis. These syndromes essentially encompass two forms, i. e. the resistance to thyroid hormones and that to TSH action. The contribution of molecular biology has been fundamental in understanding the etiology of these different thyroid disorders and led to the discovery of new pathogenetic mechanisms, e. g. the dominant negative effects of a mutant protein on the normal one. In this ... Read more
Product Details
Format
Paperback
Publication date
2012
Publisher
Springer-Verlag New York Inc. United States
Number of pages
206
Condition
New
Series
Endocrine Updates
Number of Pages
198
Place of Publication
New York, NY, United States
ISBN
9781475710656
SKU
V9781475710656
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
Reviews for Syndromes of Hormone Resistance on the Hypothalamic-Pituitary-Thyroid Axis
"Syndromes of Hormone Resistance on the Hypothalamic-Pituitary-Thyroid Axis is a tour-de force by expert authors in the field of thyroid hormone action. Using clinical syndromes of thyroid hormone and TSH resistance, they explore the fundamental mechanisms for thyroid hormone structure-function defects and translate these fascinating molecular observations into an understanding of the pathogenesis of human disease. Endocrinologists, internists, pediatricians and ... Read more