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Hongzhe Sun - ABC Transporters and Multidrug Resistance - 9780470227343 - V9780470227343
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ABC Transporters and Multidrug Resistance

€ 171.12
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Description for ABC Transporters and Multidrug Resistance Hardcover. This book gathers present knowledge on the involvement of ABC transporters in drug transport and resistance. Bringing together updated information from an otherwise-scattered field of scientific literature, this resource helps researchers in pharmaceutical science in discovering drugs able to counteract multidrug resistance in diseases like cancer. Editor(s): Boumendjel, Ahcene; Boutonnat, Jean; Robert, Jacques. Series: Wiley Series in Drug Discovery and Development. Num Pages: 460 pages, Illustrations. BIC Classification: MMG; PSBC. Category: (P) Professional & Vocational; (UP) Postgraduate, Research & Scholarly. Dimension: 233 x 163 x 28. Weight in Grams: 780.
A comprehensive review of the most current scientific research on ABC transporters and multidrug resistance

ATP-binding cassette transporter genes (ABC transporters) are known to play a crucial role in the development of multidrug resistance (MDR). MDR is the ability of pathologic cells, such as tumors, to withstand chemicals designed to target and destroy such cells. In MDR, patients who are on medication eventually develop resistance to not only the drug they are taking, but to several different types of drugs.

ABC Transporters and Multidrug Resistance offers an essential resource for pharmaceutical researchers who are working to discover drugs to ... Read more

This comprehensive volume provides an overview on the description of the structure, the genome, normal tissue expression, physiological aspect, and mechanism of action of the ABC protein. The expert contributors explore the expression, detection, and implications of ABC proteins in hematological malignancies and solid tumors and ABC proteins and pathogenic microorganisms. This volume also explains MDR modulation through inhibition of ABC transporters and the design of inhibitors and mechanism of action. In addition, the book offers essential information on the biological and clinical aspect of multidrug resistance.

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Product Details

Format
Hardback
Publication date
2009
Publisher
John Wiley and Sons Ltd United Kingdom
Number of pages
460
Condition
New
Series
Wiley Series in Drug Discovery and Development
Number of Pages
480
Place of Publication
New York, United States
ISBN
9780470227343
SKU
V9780470227343
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15

About Hongzhe Sun
Ahcéne Boumendjel is Professor of Medicinal Chemistry at the University of Grenoble School of Pharmacy, France. Jean Boutonnat is an Assistant Professor and Hospital Practitioner at the Grenoble Medical School and Université Joseph Fourier of Grenoble, France. Jacques Robert is Professor and Head of the Laboratory of Pharmacology of Anticancer Agents at Institut Bergonié and Université Victor ... Read more

Reviews for ABC Transporters and Multidrug Resistance
"The book is both interesting for both novice and experienced researches in the field." (ChemMedChem, July 2010)

Goodreads reviews for ABC Transporters and Multidrug Resistance


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