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Claudiu T. Supuran - Drug Design of Zinc-Enzyme Inhibitors - 9780470275009 - V9780470275009
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Drug Design of Zinc-Enzyme Inhibitors

€ 266.68
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Description for Drug Design of Zinc-Enzyme Inhibitors Hardcover. The book gives students and young researchers a resource on zinc enzymes, some of which were intensively studied for more than six decades and translated into model success stories of the pharmaceutical industry. Editor(s): Supuran, Claudiu T.; Winum, Jean-Yves. Series Editor(s): Wang, Binghe. Series: Wiley Series in Drug Discovery and Development. Num Pages: 1022 pages, Illustrations. BIC Classification: MMG; TDCW. Category: (P) Professional & Vocational. Dimension: 239 x 161 x 53. Weight in Grams: 1586.
Brings together functional and structural informationrelevant to the design of drugs targeting zinc enzymes

The second most abundant transition element in living organisms, zinc spans all areas of metabolism, with zinc-containing proteins offering both established and potential drug targets. Drug Design of Zinc-Enzyme Inhibitors brings together functional and structural information relevant to these zinc-containing targets. With up-to-date overviews of the latest developments field, this unique and comprehensive text enables readers to understand zinc enzymes and evaluate them in a drug design context.

With contributions from the leaders of today's research, Drug Design of Zinc-Enzyme Inhibitors covers such key topics ... Read more

  • Major drug targets like carbonic anhydrases, matrix metalloproteinases, bacterial proteases, angiotensin-converting enzyme, histone deacetylase, and APOBEC3G

  • Roles of recently discovered zinc-containing isozymes in cancer, obesity, epilepsy, pain management, malaria, and other conditions

  • Cross reactivity of zinc-enzyme inhibitors and activators

  • The extensive use of X-ray crystallography and QSAR studies for understanding zinc-containing proteins

  • Clinical applications

An essential resource for the discovery and development of new drug molecules, Drug Design of Zinc-Enzyme Inhibitors gives researchers, professionals, students, and academics the foundation to understand and work with zinc enzyme inhibitors and activators.

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Product Details

Format
Hardback
Publication date
2009
Publisher
John Wiley and Sons Ltd United Kingdom
Number of pages
1022
Condition
New
Series
Wiley Series in Drug Discovery and Development
Number of Pages
1040
Place of Publication
New York, United States
ISBN
9780470275009
SKU
V9780470275009
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15

About Claudiu T. Supuran
Claudiu T. Supuran is a professor in the Department of Chemistry at the University of Florence, Italy. His main research interests include medicinal chemistry, design of enzyme inhibitors and activators, X-ray crystallography of metallo-enzymes, and metal complexes with biologically active ligands (metal-based drugs). He has published more than 400 original research papers in these fields. Jean-Yves Winum is an ... Read more

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