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Towards Dual and Targeted Cancer Therapy with Novel Phthalocyanine-Based Photosensitizers
Janet T. F. Lau
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Description for Towards Dual and Targeted Cancer Therapy with Novel Phthalocyanine-Based Photosensitizers
Paperback. This book explores different approaches to develop phthalocyanine-based photosensitizers toward dual and targeted photodynamic therapy (PDT), with a view to improving their specific delivery to cancerous tissues and efficiency in PDT. Series: Springer Theses. Num Pages: 202 pages, biography. BIC Classification: MJCL; PNR; PSB. Category: (G) General (US: Trade). Dimension: 235 x 155 x 11. Weight in Grams: 320.
Janet Lau's thesis describes her studies into the use of phthalocyanine-based photosensitizers in combined chemo- and photodynamic therapy (PDT) and targeted PDT. In order to carry out this study, Lau uses several approaches: conjugation with a chemotherapeutic oxaliplatin derivative, use of a polyamine ligand 2 with a view to targeting the polyamine transporters over-expressed in tumor cells, and employment of a quencher that can inhibit their photodynamic activity but can still be removed under a tumor-associated environment such as low pH and high thiol concentration. This thesis reports dual activatable photosensitizers for the first time. Overall the studies included are ... Read more
Janet Lau's thesis describes her studies into the use of phthalocyanine-based photosensitizers in combined chemo- and photodynamic therapy (PDT) and targeted PDT. In order to carry out this study, Lau uses several approaches: conjugation with a chemotherapeutic oxaliplatin derivative, use of a polyamine ligand 2 with a view to targeting the polyamine transporters over-expressed in tumor cells, and employment of a quencher that can inhibit their photodynamic activity but can still be removed under a tumor-associated environment such as low pH and high thiol concentration. This thesis reports dual activatable photosensitizers for the first time. Overall the studies included are ... Read more
Product Details
Format
Paperback
Publication date
2015
Publisher
Springer International Publishing AG Switzerland
Number of pages
202
Condition
New
Series
Springer Theses
Number of Pages
180
Place of Publication
Cham, Switzerland
ISBN
9783319033167
SKU
V9783319033167
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
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