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Cyclin Dependent Kinase (CDK) Inhibitors
. Ed(S): Vogt, Peter K.; Reed, Stephen I.
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Description for Cyclin Dependent Kinase (CDK) Inhibitors
Paperback. Editor(s): Vogt, Peter K.; Reed, Stephen I. Series: Current Topics in Microbiology and Immunology. Num Pages: 181 pages, 1 black & white illustrations, 7 black & white tables, biography. BIC Classification: MJCL; MJCM; PSB; PSF. Category: (P) Professional & Vocational. Dimension: 235 x 155 x 10. Weight in Grams: 294.
More than 10 years ago, the discovery of cyclin-dependent ki nases (Cdks) ushered in a new era in the understanding of cell proliferation and its control. Not only were both of the known cell cycle transitions, from G 1 to S phase and G2 to M phase, found to be dependent on these protein kinases, but the reg ulatory assumption intrinsic to cyclin-dependent kinases, a stable inactive catalytic subunit (the Cdk) and an unstable requisite positive regulatory activating subunit (the cyclin), led to a simple model for cell cycle control. Modulation of cyclin accumulation, and thereby Cdk activation, was proposed ... Read more
More than 10 years ago, the discovery of cyclin-dependent ki nases (Cdks) ushered in a new era in the understanding of cell proliferation and its control. Not only were both of the known cell cycle transitions, from G 1 to S phase and G2 to M phase, found to be dependent on these protein kinases, but the reg ulatory assumption intrinsic to cyclin-dependent kinases, a stable inactive catalytic subunit (the Cdk) and an unstable requisite positive regulatory activating subunit (the cyclin), led to a simple model for cell cycle control. Modulation of cyclin accumulation, and thereby Cdk activation, was proposed ... Read more
Product Details
Format
Paperback
Publication date
2011
Publisher
Springer-Verlag Berlin and Heidelberg GmbH & Co. KG Germany
Number of pages
181
Condition
New
Series
Current Topics in Microbiology and Immunology
Number of Pages
169
Place of Publication
Berlin, Germany
ISBN
9783642719431
SKU
V9783642719431
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
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