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Genetic and Molecular Epidemiology of Multiple Myeloma
Suzanne . Ed(S): Lentzsch
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Description for Genetic and Molecular Epidemiology of Multiple Myeloma
Paperback. This exploration of the role of protein translation in multiple myeloma covers recent advances in oncogenomic research that further our understanding of the disease's molecular pathogenesis, and discusses the emerging technique of epigenetic gene silencing. Editor(s): Lentzsch, Suzanne. Num Pages: 132 pages, biography. BIC Classification: MFN; MJCL; PSF. Category: (G) General (US: Trade). Dimension: 235 x 155 x 7. Weight in Grams: 221.
Multiple myeloma is a plasma cell malignancy characterized by complex heterogenous cytogenetic abnormalities that accounts for 1.4% of all cancers, and approximately 10% of hematologic malignancies. The clinical manifestations of multiple myeloma include lytic bone lesions, cytopenia, hypercalcemia, renal dysfunction, hyperviscosity of the blood, immunodeficiency, and peripheral neuropathy. Based on the clinical and genetic data, probably all cases of multiple myeloma arise from an asymptomatic monoclonal gammopathy of unknown significance. The exact mechanism of the transition from MGUS to overt multiple myeloma is still not well understood. Recent oncogenomic studies have further advanced our understanding of the molecular pathogenesis of ... Read more
Multiple myeloma is a plasma cell malignancy characterized by complex heterogenous cytogenetic abnormalities that accounts for 1.4% of all cancers, and approximately 10% of hematologic malignancies. The clinical manifestations of multiple myeloma include lytic bone lesions, cytopenia, hypercalcemia, renal dysfunction, hyperviscosity of the blood, immunodeficiency, and peripheral neuropathy. Based on the clinical and genetic data, probably all cases of multiple myeloma arise from an asymptomatic monoclonal gammopathy of unknown significance. The exact mechanism of the transition from MGUS to overt multiple myeloma is still not well understood. Recent oncogenomic studies have further advanced our understanding of the molecular pathogenesis of ... Read more
Product Details
Format
Paperback
Publication date
2015
Publisher
Springer-Verlag New York Inc. United States
Number of pages
132
Condition
New
Number of Pages
125
Place of Publication
New York, United States
ISBN
9781489998651
SKU
V9781489998651
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Ref
99-15
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