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. Ed(S): Gullberg, Donald (Uppsala University, Sweden) - I Domains in Integrins - 9780306478369 - V9780306478369
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I Domains in Integrins

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Description for I Domains in Integrins Hardback. In vertebrates, the integrin family includes 24 members. This book discusses ligand binding, signalling properties, knock-out phenotypes and possible involvement in disease. It comprehensively reviews the knowledge about I domains in integrins and serves as a useful reference book for scientists in this field. Editor(s): Gullberg, Donald (Uppsala University, Sweden). Series: Molecular Biology Intelligence Unit. Num Pages: 196 pages, biography. BIC Classification: MFGM; PSB. Category: (P) Professional & Vocational; (UP) Postgraduate, Research & Scholarly; (UU) Undergraduate. Dimension: 229 x 152 x 19. Weight in Grams: 482.
In vertebrates, the integrin family includes 24 members. As the alpha-chains were sequenced, some were observed to have an inserted domain similar to the A domain in several matrix and complement proteins. This inserted ligand binding domain is interactive and was called the I domain in integrins. More recently structural data have shown that an integrin beta-chain also contains an I domain. Nine of the currently known 18 alpha-chains contain an I domain.
This book systematically goes through the current knowledge about these integrins, including the newest additions to the integrin family, the collagen-binding alpha10beta1 and alpha11beta1 integrins. The ... Read more

Product Details

Format
Hardback
Publication date
2003
Publisher
Springer Science+Business Media United States
Number of pages
196
Condition
New
Series
Molecular Biology Intelligence Unit
Number of Pages
186
Place of Publication
, United States
ISBN
9780306478369
SKU
V9780306478369
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15

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