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Integrin Protocols
Anthony R. . Ed(S): Howlett
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Description for Integrin Protocols
Paperback. Editor(s): Howlett, Anthony R. Series: Methods in Molecular Biology. Num Pages: 296 pages, 24 black & white illustrations, biography. BIC Classification: PSF. Category: (P) Professional & Vocational. Dimension: 229 x 152 x 17. Weight in Grams: 459.
It is now widely accepted that the extracellular matrix (ECM) is a key determinant of tissue-specific gene expression. Signals provided by ECM are transduced by integrins, a large and growing superfamily of transmembrane heterodimeric cell surface receptors that link the ECM to structural and fu- tional elements within the cell. A wide range of cellular phenotypes have been shown to be regulated by integrins, including growth, differentiation, mig- tion, invasion, angiogenesis, and apoptosis. Furthermore, abnormalities of integrin expression and function have been implicated in the etiology of va- ous pathologic conditions, including cardiovascular disease, inflammatory disorders, and cancer. Thus integrins ... Read more
It is now widely accepted that the extracellular matrix (ECM) is a key determinant of tissue-specific gene expression. Signals provided by ECM are transduced by integrins, a large and growing superfamily of transmembrane heterodimeric cell surface receptors that link the ECM to structural and fu- tional elements within the cell. A wide range of cellular phenotypes have been shown to be regulated by integrins, including growth, differentiation, mig- tion, invasion, angiogenesis, and apoptosis. Furthermore, abnormalities of integrin expression and function have been implicated in the etiology of va- ous pathologic conditions, including cardiovascular disease, inflammatory disorders, and cancer. Thus integrins ... Read more
Product Details
Format
Paperback
Publication date
2013
Publisher
Humana Press Inc. United States
Number of pages
296
Condition
New
Series
Methods in Molecular Biology
Number of Pages
296
Place of Publication
Totowa, NJ, United States
ISBN
9781489943415
SKU
V9781489943415
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
Reviews for Integrin Protocols
"Integrin Protocols aims to provide a hand-book of methods for the study of integrins. Many of the essential techniques are covered, with sections ranging from the relatively straight-forward (immunoblotting) to the highly complex (phage display and knock-outs)...Over half of the sections are by major figures in the integrin field, thus giving the book considerable authority..."-Cell Biology International 2000