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Mass Spectrometry in Drug Metabolism
Alberto Frigerio
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Description for Mass Spectrometry in Drug Metabolism
Paperback. Num Pages: 532 pages, biography. BIC Classification: MMG; PNFS; PSB. Category: (G) General (US: Trade). Dimension: 244 x 170 x 28. Weight in Grams: 933.
When a dose of drug is administered, three main phases of drug action may be distingushed. In the "pharmaceutical" phase the dosage form disintegrates, the active substance dissolves and becomes available for absorption. The second phase ("pharmaco kinetic" phase) includes absorption, distribution, metabolism, and excretion. That fraction of the dose which finally reaches the circulation after absorption will be available for biological action in the third, or "pharmacodynamic" phase when the drug reaches the target tissues and a drug-receptor interaction takes place. The objectives in studies of drug metabolism are: (a) to identify the pathways by which drugs are transformed ... Read more
When a dose of drug is administered, three main phases of drug action may be distingushed. In the "pharmaceutical" phase the dosage form disintegrates, the active substance dissolves and becomes available for absorption. The second phase ("pharmaco kinetic" phase) includes absorption, distribution, metabolism, and excretion. That fraction of the dose which finally reaches the circulation after absorption will be available for biological action in the third, or "pharmacodynamic" phase when the drug reaches the target tissues and a drug-receptor interaction takes place. The objectives in studies of drug metabolism are: (a) to identify the pathways by which drugs are transformed ... Read more
Product Details
Format
Paperback
Publication date
2011
Publisher
Springer-Verlag New York Inc. United States
Number of pages
532
Condition
New
Number of Pages
532
Place of Publication
New York, NY, United States
ISBN
9781461341536
SKU
V9781461341536
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
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