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Mitochondrial DNA Mutations in Aging, Disease and Cancer
Keshav K. . Ed(S): Singh
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Description for Mitochondrial DNA Mutations in Aging, Disease and Cancer
Paperback. Editor(s): Singh, Keshav K. Num Pages: 412 pages, 42 black & white illustrations, 6 colour illustrations, biography. BIC Classification: MBGR; MFN; MJCL; PSB; PSF. Category: (P) Professional & Vocational. Dimension: 244 x 170 x 23. Weight in Grams: 747.
Many human genetic diseases associated with blood, brain, colon, ear, eye, heart, kidney, liver, muscle, and pancreas are caused by mutations in mitochondrial DNA. Mutations in DNA can result in defects of the electron transport complexes, intermediates of the tricarboxylic acid cycle and substrate transport. The clinical manifestation of these diseases often involves muscle and the nervous system. Mitochondrial DNA mutations have now been associated with aging as well as age-related degenerative diseases such as Parkinson's, Alzheimer's, and Huntington's diseases. Changes in structure, function, and a number of mitochondria play an important role in carcinogenesis. Furthermore, the role of mitochondria ... Read more
Many human genetic diseases associated with blood, brain, colon, ear, eye, heart, kidney, liver, muscle, and pancreas are caused by mutations in mitochondrial DNA. Mutations in DNA can result in defects of the electron transport complexes, intermediates of the tricarboxylic acid cycle and substrate transport. The clinical manifestation of these diseases often involves muscle and the nervous system. Mitochondrial DNA mutations have now been associated with aging as well as age-related degenerative diseases such as Parkinson's, Alzheimer's, and Huntington's diseases. Changes in structure, function, and a number of mitochondria play an important role in carcinogenesis. Furthermore, the role of mitochondria ... Read more
Product Details
Format
Paperback
Publication date
2013
Publisher
Springer-Verlag Berlin and Heidelberg GmbH & Co. KG Germany
Number of pages
412
Condition
New
Number of Pages
412
Place of Publication
Berlin, Germany
ISBN
9783662125113
SKU
V9783662125113
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
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