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P53 Protocols
. Ed(S): Deb, Sumitra; Deb, Swati Palit
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Description for P53 Protocols
Hardback. Editor(s): Deb, Sumitra; Deb, Swati Palit. Series: Methods in Molecular Biology. Num Pages: 280 pages, biography. BIC Classification: PSB. Category: (P) Professional & Vocational; (UP) Postgraduate, Research & Scholarly; (UU) Undergraduate. Dimension: 229 x 152 x 20. Weight in Grams: 1340.
Since the discovery of p53 as a tumor suppressor, numerous methods have evolved to reveal the unique structural features and biochemical functions of this protein. Several unique properties of p53 posed a challenge to understa- ing its normal function in the initial phase of its research. The low levels of p53 in normal cells, its stabilization under situations of genotoxic stress, induction of growth arrest, and apoptosis with stabilization of the protein, obstructed the visibility of its normal, unmutated function. The property of p53 that can sense a promoter and transactivate or inhibit is still not well understood. It is ... Read more
Since the discovery of p53 as a tumor suppressor, numerous methods have evolved to reveal the unique structural features and biochemical functions of this protein. Several unique properties of p53 posed a challenge to understa- ing its normal function in the initial phase of its research. The low levels of p53 in normal cells, its stabilization under situations of genotoxic stress, induction of growth arrest, and apoptosis with stabilization of the protein, obstructed the visibility of its normal, unmutated function. The property of p53 that can sense a promoter and transactivate or inhibit is still not well understood. It is ... Read more
Product Details
Format
Hardback
Publication date
2003
Publisher
Humana Press Inc. United States
Number of pages
280
Condition
New
Series
Methods in Molecular Biology
Number of Pages
280
Place of Publication
Totowa, NJ, United States
ISBN
9781588291066
SKU
V9781588291066
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
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