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Patch-Clamp Applications and Protocols
. Ed(S): Boulton, Alan A.; Baker, Glen B.; Walz, Wolfgang
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Description for Patch-Clamp Applications and Protocols
Hardback. Covers the techniques for measuring and recording directly activity within a cell. This book offers developments associated with the technology of path-clamp electrodes, of cell-free ion-channel recording, and of the whole-cell patch clamp technique. It also covers the loose patch-clamp technique, single-channel recording, and more. Editor(s): Boulton, Alan A.; Baker, Glen B.; Walz, Wolfgang. Series: Neuromethods. Num Pages: 316 pages, biography. BIC Classification: PSAN; PSF. Category: (P) Professional & Vocational; (UP) Postgraduate, Research & Scholarly; (UU) Undergraduate. Dimension: 235 x 155 x 23. Weight in Grams: 728.
E. Neher and B. Sakman were the first to monitor the opening and closing of single ion channels and membranes by conductance measurements. In 1976, they used firepolished micropipets with a tip diameter of 3-5 pm to record currents from a small patch of the membranbe of sk- etal muscles, thereby decreasing background membrane noise. In order to reduce the dominant source of background noise-the leakage shunt under the pipet rim between m- the muscle membrane had to be treated brane and gla- enzymatically. Despite these early limitations, a new te- nique was born -the patch-clamp technique. The final bre- ... Read more
E. Neher and B. Sakman were the first to monitor the opening and closing of single ion channels and membranes by conductance measurements. In 1976, they used firepolished micropipets with a tip diameter of 3-5 pm to record currents from a small patch of the membranbe of sk- etal muscles, thereby decreasing background membrane noise. In order to reduce the dominant source of background noise-the leakage shunt under the pipet rim between m- the muscle membrane had to be treated brane and gla- enzymatically. Despite these early limitations, a new te- nique was born -the patch-clamp technique. The final bre- ... Read more
Product Details
Format
Hardback
Publication date
1995
Publisher
Humana Press Inc. United States
Number of pages
316
Condition
New
Series
Neuromethods
Number of Pages
316
Place of Publication
Totowa, NJ, United States
ISBN
9780896033115
SKU
V9780896033115
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
Reviews for Patch-Clamp Applications and Protocols
...valuable...because much of the book is written with a view to helping with the design of experiments and improving the quality of patch-clamp recordings...a useful addition and update to the technical literature on the patch-clamp technique. -Trends in Pharmacological Sciences