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Tumor Suppressor Genes
Wafik S. . Ed(S): El-Deiry
€ 200.02
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Description for Tumor Suppressor Genes
Hardback. Explores the cell biology and biochemical function of the tumor suppressor genes, as well as its physiological role in vivo. This volume details the physical methods used to understand the function of tumor suppressor genes. It discusses in vivo approaches such as studies in yeast, Drosophilia, mice, and human tumors. Editor(s): El-Deiry, Wafik S. Series: Methods in Molecular Biology. Num Pages: 657 pages, biography. BIC Classification: MFN; MJCL; PDN. Category: (P) Professional & Vocational; (UP) Postgraduate, Research & Scholarly; (UU) Undergraduate. Dimension: 254 x 178 x 36. Weight in Grams: 1385.
It has become clear that tumors result from excessive cell proliferation and a corresponding reduction in cell death caused by the successive accumulation of mutations in key regulatory target genes over time. During the 1980s, a number of oncogenes were characterized, whereas from the 1990s to the present, the emp- sis has shifted to tumor suppressor genes (TSGs). It has become clear that oncogenes and TSGs function in the same pathways, providing positive and negative growth regulatory activities. The signaling pathways controlled by these genes involve virtually every process in cell biology, including nuclear events, cell cycle, cell death, cytoskeletal, ... Read more
It has become clear that tumors result from excessive cell proliferation and a corresponding reduction in cell death caused by the successive accumulation of mutations in key regulatory target genes over time. During the 1980s, a number of oncogenes were characterized, whereas from the 1990s to the present, the emp- sis has shifted to tumor suppressor genes (TSGs). It has become clear that oncogenes and TSGs function in the same pathways, providing positive and negative growth regulatory activities. The signaling pathways controlled by these genes involve virtually every process in cell biology, including nuclear events, cell cycle, cell death, cytoskeletal, ... Read more
Product Details
Format
Hardback
Publication date
2003
Publisher
Humana Press Inc. United States
Number of pages
657
Condition
New
Series
Methods in Molecular Biology
Number of Pages
657
Place of Publication
Totowa, NJ, United States
ISBN
9780896039872
SKU
V9780896039872
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
Reviews for Tumor Suppressor Genes
"The book will prove a great help to everybody who would like to enter the field of experimental and or clinical research. Those who are interested in basic understanding microbiology of cancer will enjoy this as well." -Neoplasma