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Signalling from Internalised Growth Factor Receptors
Inger H. . Ed(S): Madshus
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Description for Signalling from Internalised Growth Factor Receptors
Hardback. This title concentrates on how growth factor receptors are down-regulated by endocytosis and intracellular trafficking. The authors discuss what is currently understood about the effect of cellular microenvironments on signal transduction. Editor(s): Madshus, Inger H. Series: Current Topics in Microbiology and Immunology. Num Pages: 199 pages, 27 black & white illustrations, 4 colour illustrations, biography. BIC Classification: PS. Category: (P) Professional & Vocational; (U) Tertiary Education (US: College). Dimension: 235 x 155 x 13. Weight in Grams: 400.
Mammalian cells are to a large extent controlled by the environment. Dif- fusible factors (growth factors, cytokines, and hormones) released by oth- er cells in the body bind to and activate receptors localized at the cell sur- face. In the case of the fibroblast growth factor receptor, there seems to be receptors both at the plasma membrane and in the nucleus. Cellular recep- tors control growth, apoptosis, immune function, differentiation, develop- and upon dysregulation, cancer progression and metastasis. Upon li- ment, gand binding, most receptors are internalized. However, the mechanisms of endocytosis are diverse, and receptors are taken into cells ... Read more
Mammalian cells are to a large extent controlled by the environment. Dif- fusible factors (growth factors, cytokines, and hormones) released by oth- er cells in the body bind to and activate receptors localized at the cell sur- face. In the case of the fibroblast growth factor receptor, there seems to be receptors both at the plasma membrane and in the nucleus. Cellular recep- tors control growth, apoptosis, immune function, differentiation, develop- and upon dysregulation, cancer progression and metastasis. Upon li- ment, gand binding, most receptors are internalized. However, the mechanisms of endocytosis are diverse, and receptors are taken into cells ... Read more
Product Details
Format
Hardback
Publication date
2004
Publisher
Springer-Verlag Berlin and Heidelberg GmbH & Co. KG Germany
Number of pages
199
Condition
New
Series
Current Topics in Microbiology and Immunology
Number of Pages
190
Place of Publication
Berlin, Germany
ISBN
9783540210382
SKU
V9783540210382
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
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