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Steric Fit in Quantitative Structure-Activity Relations
Balaban, A.T.; Chiriac, A.; Motoc, I.; Simon, Z.
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Description for Steric Fit in Quantitative Structure-Activity Relations
paperback. Series: Lecture Notes in Chemistry. Num Pages: 185 pages, biography. BIC Classification: PNRP. Category: (P) Professional & Vocational. Dimension: 244 x 170 x 10. Weight in Grams: 348.
Although the importance of steric fit for receptor-effector 1 interactions was recognized since Emil Fischer proposed his "lock and key" theory, the whole area of steric properties is still in a very 2-4 early stage of development. We have a fairly good idea about el- tronic and hydrophobic parameters, but it is not easy to describe ste- ric shapes of molecules without a large number of data. There are se- veral cases of good QSAR's developed for rather large series of mole- 5 cules without steric parameters - for example see papers by Hansch , 6 or Franke , but ... Read more
Although the importance of steric fit for receptor-effector 1 interactions was recognized since Emil Fischer proposed his "lock and key" theory, the whole area of steric properties is still in a very 2-4 early stage of development. We have a fairly good idea about el- tronic and hydrophobic parameters, but it is not easy to describe ste- ric shapes of molecules without a large number of data. There are se- veral cases of good QSAR's developed for rather large series of mole- 5 cules without steric parameters - for example see papers by Hansch , 6 or Franke , but ... Read more
Product Details
Format
Paperback
Publication date
1980
Publisher
Springer-Verlag Berlin and Heidelberg GmbH & Co. KG Germany
Number of pages
185
Condition
New
Series
Lecture Notes in Chemistry
Number of Pages
178
Place of Publication
Berlin, Germany
ISBN
9783540097556
SKU
V9783540097556
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
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