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Structural and Functional Characterization of the Immunoproteasome
Eva Maria Huber
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Description for Structural and Functional Characterization of the Immunoproteasome
Paperback. In this acclaimed thesis, the author uses a methodologies including X-ray crystallography, fluorescence spectroscopy and mutagenesis experiments to reveal ground-breaking and vitally influential results on the crystal structure of the murine immunoproteasome. Series: Springer Theses. Num Pages: 101 pages, 4 black & white illustrations, 29 colour illustrations, biography. BIC Classification: PSBC. Category: (P) Professional & Vocational. Dimension: 235 x 155 x 6. Weight in Grams: 174.
In this acclaimed thesis, Eva Maria Huber reveals ground-breaking results by elucidating the crystal structure of the murine immunoproteasome in complex with a selective inhibitor. Huber does this by performing multidisciplinary methodologies including X-ray crystallography, fluorescence spectroscopy and mutagenesis experiments. Her exceptional results explore the immunoproteasome complex structures and are of outstanding importance for future scientific research especially in the pharmaceutical industry. These results will enable the functional analysis of individual proteasome subunits and support the development of novel drugs for autoimmune diseases such as multiple sclerosis or rheumatoid arthritis.
In this acclaimed thesis, Eva Maria Huber reveals ground-breaking results by elucidating the crystal structure of the murine immunoproteasome in complex with a selective inhibitor. Huber does this by performing multidisciplinary methodologies including X-ray crystallography, fluorescence spectroscopy and mutagenesis experiments. Her exceptional results explore the immunoproteasome complex structures and are of outstanding importance for future scientific research especially in the pharmaceutical industry. These results will enable the functional analysis of individual proteasome subunits and support the development of novel drugs for autoimmune diseases such as multiple sclerosis or rheumatoid arthritis.
Product Details
Format
Paperback
Publication date
2016
Publisher
Springer International Publishing AG Switzerland
Number of pages
101
Condition
New
Series
Springer Theses
Number of Pages
82
Place of Publication
Cham, Switzerland
ISBN
9783319378107
SKU
V9783319378107
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
About Eva Maria Huber
Eva Huber studied biochemistry at the Technische Universität München (TUM) from 2004 till 2009. For her master studies, which were funded by the Studienstiftung des deutschen Volkes, she received the Jürgen-Manchot Studienpreis from the faculty of chemistry of the TUM. During her postgraduate studies (2009-2013) in the group of Prof. Groll at the TUM she succeeded in the elucidation of ... Read more
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