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The Ionotropic Glutamate Receptors
John Monaghan
€ 202.01
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Description for The Ionotropic Glutamate Receptors
Hardback. Fifteen contributed articles by investigators survey the dramatic increase in the understanding of receptor action that has resulted from the recent cloning of numerous ionotropic glutamate receptor subunits. Series: The Receptors. Num Pages: 379 pages, biography. BIC Classification: MJN; MMG; PSAK; PSAN; PSB. Category: (P) Professional & Vocational; (UP) Postgraduate, Research & Scholarly; (UU) Undergraduate. Dimension: 235 x 155 x 25. Weight in Grams: 744.
The field of the excitatory amino acids was born when L-glutamate and L-aspartate were found to be potent convulsants (Hayashi, 1954), and were subsequently found to excite neurons directly (Curtis, Phillis, and Watkins, 1959). Although these studies initiated the hypothesis of glutamate-mediated neurotransmission, it was noted that the ubiquitous actions of glutamate could also reflect a general, nonspecific property of glutamate on neuronal mem- branes. It was not until 20 years later that pharmacological, physiological, and biochemical studies provided convincing evidence for a neurotransmitter role for glutamate in the mammalian central nervous system (CNS). With the critical demonstration that the ... Read more
The field of the excitatory amino acids was born when L-glutamate and L-aspartate were found to be potent convulsants (Hayashi, 1954), and were subsequently found to excite neurons directly (Curtis, Phillis, and Watkins, 1959). Although these studies initiated the hypothesis of glutamate-mediated neurotransmission, it was noted that the ubiquitous actions of glutamate could also reflect a general, nonspecific property of glutamate on neuronal mem- branes. It was not until 20 years later that pharmacological, physiological, and biochemical studies provided convincing evidence for a neurotransmitter role for glutamate in the mammalian central nervous system (CNS). With the critical demonstration that the ... Read more
Product Details
Format
Hardback
Publication date
1996
Publisher
Humana Press Inc. United States
Number of pages
379
Condition
New
Series
The Receptors
Number of Pages
379
Place of Publication
Totowa, NJ, United States
ISBN
9780896034563
SKU
V9780896034563
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
Reviews for The Ionotropic Glutamate Receptors
...will be an important reference...Each chapter is worth reading in its entirety, and each provides a solid groundingin the state of research to this point...will help [to] guide us over the next six years. - Journal of Molecular Neuroscience