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The Role of Wnt Signalling in the Development of Somites and Neural Crest
Schmidt, Corina; McGonnell, Imelda; Allen, Steve; Patel, Ketan
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Description for The Role of Wnt Signalling in the Development of Somites and Neural Crest
Paperback. Series: Advances in Anatomy, Embryology and Cell Biology. Num Pages: 74 pages, 15 colour illustrations, biography. BIC Classification: PSAN. Category: (P) Professional & Vocational. Dimension: 235 x 155 x 5. Weight in Grams: 132.
1 Introduction 1. 1 Wnts and Development The f amily of Wnt genes consists of at least 19 members in vertebrates. Wnts ha v e multiple roles during normal development and aetiology of diseases (Wodarz and Nusse 1998; Moon et al. 2002, 2004). These genes encode for glycoproteins that are released in the intercellular space, acting as intercellular mediators (Moon et al. 1997). By binding to their special receptors, the Frizzled (Fz) receptors, they are able to activate at least three different pathways: the canonical, the non-canonical and the Ca 2+ pathway (Fig. 1 ). The Wnt family has been ... Read more
1 Introduction 1. 1 Wnts and Development The f amily of Wnt genes consists of at least 19 members in vertebrates. Wnts ha v e multiple roles during normal development and aetiology of diseases (Wodarz and Nusse 1998; Moon et al. 2002, 2004). These genes encode for glycoproteins that are released in the intercellular space, acting as intercellular mediators (Moon et al. 1997). By binding to their special receptors, the Frizzled (Fz) receptors, they are able to activate at least three different pathways: the canonical, the non-canonical and the Ca 2+ pathway (Fig. 1 ). The Wnt family has been ... Read more
Product Details
Format
Paperback
Publication date
2008
Publisher
Springer-Verlag Berlin and Heidelberg GmbH & Co. KG Germany
Number of pages
74
Condition
New
Series
Advances in Anatomy, Embryology and Cell Biology
Number of Pages
64
Place of Publication
Berlin, Germany
ISBN
9783540777267
SKU
V9783540777267
Shipping Time
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Ref
99-15
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